At RVHS, the REB's clear moral foundation of clinical equipoise requires that people will not be disadvantaged by research participation. The rights, safety and wellbeing of the clinical trial participants are the most important consideration, even above the interests of science. The basic ethical principles of RVHS' REB are to do no harm (non-maleficience), to disclose all facts, to communicate truthfully (veracity) and to conduct valid research.

The RVHS, REB will act in compliance with all laws, policies, standards and guidelines governing human research, which are applicable to a submitted research study including but not limited to the Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans, the World Medical Association Declaration of Helinski, and the Personal Health Information Protection Act.